‘The 2nd is nanopores, which happens to be our oldest line of research and that has now led to DNA sequencers determined by nanopores. We pull specific DNA strands via a nanopore and may then read from the nucleotide sequence. Incredibly lately, we even managed to examine out only one protein for The 1st time working with This method. But this line of investigation is not simply about establishing equipment, but in addition about actual biological queries.

It had been only within the nineties though, when nanotechnology experienced Innovative to a stage where solitary molecules can be manipulated, that the initial experimental equipment began to seem.

Multicolor imaging on the bacterial nucleoid and cell division proteins with blue, orange, and near-infrared fluorescent proteins

Sculpting nano-electrodes having a transmission electron beam for electrical and geometrical characterization of nanoparticles.

That is a aspiration of mine and we established to work by using a delicious dose of naivety. That is a thing that will probably produce impressive results in the for a longer time expression, but that doesn't make a difference. You should not only want to operate over the issues of tomorrow, but also within the inquiries of your day right after tomorrow.’

Our investigate ranges within the biophysics of DNA to artificial cells and outside of. You should take a look down below within the spectrum of our present-day jobs.

We use nanofabricated microfluidic structures to pattern spatial boundaries for bacteria and biomimetic vesicles with reconstituted protein networks and this evaluate the elemental purpose of spatial confinement for the molecular and cellular degree. Our tasks consist of the following:

Dynamic ParB–DNA interactions initiate and keep a partition condensate for bacterial chromosome segregation

What if, in lieu of employing standard major-down silicon electronics, transistors may be constructed from The underside up making use of one organic and natural molecules as the switching things? This idea, which grew to become The premise of right now’s industry of molecular electronics, 1st emerged in the nineteen seventies.

It was in the course of this era that Dekker completed exploration on magnetic spin units and on noise in superconductors and semiconductors.

Testing pseudotopological and nontopological types for SMC-pushed DNA loop extrusion against roadblock-traversal experiments

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Dekker heeft fundamentele ontdekkingen gedaan op het gebied van koolstof nanobuisjes. Mede vanwege deze werkzaamheden is hij al jaren de meest geciteerde fysicus in Nederland. Tegenwoordig onderzoekt hij fulfilled enkel-molecuultechnieken de biofysica van moleculen in de biologische cel. Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond clever design and style in 2005. (nl)